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bomj-vol22-issue-1

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January - June 2025
Volume 22 | Issue 1  

This journal has been online since Saturday, April 05, 2013

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ORIGINAL ARTICLE


 
 
 

Prevalence and Antibiotic Resistance Patterns of Campylobacter jejuni and Campylobacter coli from Children with Diarrhoea at University of Maiduguri Teaching Hospital Maiduguri, Nigeria

Danjuma AA, Baba AS, Yusuf HM, Manasa YS, James AA, Gideon DM.

Background: Campylobacter species have been recognised as a leading cause of acute bacterial gastroenteritis in humans. Owing to the high prevalence of resistance, antibiotics are losing effectiveness in clinical treatment of human campylobacteriosis. Objective: This study was conducted to determine the prevalence and antibiotic resistance pattern of Campylobacter. Methods: Stool specimen was suspended in Campylobacter enrichment broth and incubated at 42 0 C for 48 hours in microaerophilic conditions. Campylobacter agar containing cefoperazone and vancomycin was inoculated with 5µl of the enrichment broth and incubated at 42 0 C for 48 h as above. Campylobacter jejuni and C. coli were identied using conventional bacteriological methods and confirmed with molecular techniques. Sensitivity testing was performed using disc diffusion method. Results: Out of the 250 stool samples from children with diarrhoea tested, 37 (14.8.%) was positive for Campylobacter species. Of the 100 samples from non-diarrhoea children examined, two (2%) was positive for Campylobacter species. Campylobacter coli (56.8%) was more frequently isolated compared to C. jejuni (43.2%). Most of the isolates were from children aged 19 – 24 months. Males (17.6 %) were more affected than females (11.8%). Antibiotic sensitivity testing results revealed high resistance rates among the isolates to erythromycin, ciprooxacin, nalidixic acid, tetracycline, gentamicin, streptomycin, cotrimoxazole and azithromycin and no resistance to chloramphenicol. Multidrug resistance (resistance to > 3 antibiotics) was observed in 53.8% of C. coli and 46.2% of C. jejuni isolates. Conclusion: The ndings of this study underscore the signicance of Campylobacter infections as a major public health concern in paediatric populations in Maiduguri.

Keywords: Campylobacter, prevalence, Antibiotic resistance, diarrhoea, Maiduguri

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ORIGINAL ARTICLE


 
 
 

The Prevalence of Histopathologically Diagnosed Uterine Leiomyomas in a Teaching Hospital: A Cross-Sectional Study

Adekunle AA¹, Ayo-Aderibigbe O¹, Rasheed MW², Idowu NA³, Sabageh D¹, Afolayan EOA

Background: Uterine leiomyoma is a the most common benign gynaecological tumour seen in women of reproductive age. Aim : This study aims to determine the frequency and age distribution of histologically diagnosed cases of uterine leiomyomas. Method : This was a cross-sectional retrospective review of histologically diagnosed leiomyoma at the Department of Morbid Anatomy, LAUTECH Teaching Hospital (LTH), Ogbomosho between January 2012 and December 2016. The age of patients, nature of specimens, and presenting symptoms were extracted from request cards. The data obtained was analyzed using both Microsoft Excel and Statistical Package for Social Sciences 23.0 (SPSS version 23.0). Results: The mean age of patients presenting with uterine leiomyoma was 40.5 years (SD=±10.1) with the peak age incidence in the fourth decade with a total number of 78(40.6%) cases. Menorrhagia and abdominal mass were the most common presenting complaints accounting for 117(60.9%) and 101 (52.6%) of cases respectively. Conclusion : Uterine leiomyoma is a benign neoplasm of smooth muscle origin commonly seen in women of reproductive age and abnormal uterine bleeding was the commonest presenting complaint.

 

Keywords: Leiomyoma, age, frequency, prevalence, histopathology

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ORIGINAL ARTICLE


 

Knowledge and Risks Perception of Sexually Transmitted Diseases Among Secondary School Students in Bauchi Metropolis, Northeast, Nigeria

Musa A, 1 Abba U, 2 Gaini FM, 3 Mato MN, 3 Bappah MY, 3 Jibril MB, 4

Background: Abdominal ultrasonography is an essential imaging modality in diagnosing patients with acute appendicitis. Its major advantages include high diagnostic accuracy, availability, affordability, and excellent safety prole relative to other imaging modalities with few limitations in children. Clinical diagnosis of acute appendicitis and the modied

Background: Sexually transmitted diseases (STDs) are diseases that spread mainly through sexual activities with some exceptions which can spread via other routes. These diseases frequently go undetected and untreated with consequent serious reproductive morbidity and mortality. This study determined the knowledge and risks perception of STDs among secondary school students in Bauchi metropolis, Northeastern Nigeria.

Methods: A cross-sectional study was carried out among 332 senior secondary school students in Bauchi metropolis. A semi-structured questionnaire was used to collect data on knowledge and risks perception on STDs and analyzed using Statistical product and service solutions (SPSS version 23.0). Alpha level of signicance was set at 0.05. Results : The mean age and standard deviation of the respondents was 16.25±1.714, more than half (59%) of the respondents were males and 51.2% the respondents were from senior secondary school (SSS1). The participants were mainly Hausa (66%) and Muslims (95%). The proportion of students that previously tested positive for STDs was 20.2% and the level of good knowledge and good perception were 82.5% and 62.3% of STDs respectively among the students. Factors associated with previously testing positive for STDs among secondary school students were: gender, category of school, nature of the school and the care/supervisor of the respondents. While gender, tribes and nature of the school were also factors associated with knowledge of STDs, the signicant predictor of knowledge of STDs was tribe [OR =2.8, CI (1.22 – 6.43)]. Conclusion: There was good knowledge, good perception and low proportion of students that previously tested positive for STDs in Bauchi metropolis and there was association between knowledge with tribe, gender, and other factors. Adolescent sex education and strengthening of screening services may further reduce the risks of STDs in addition to detecting students with STDs.

Keywords: Knowledge, STDs, perception, adolescents, Bauchi

 

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ORIGINAL ARTICLE


 
 
 

Assessment of Oxidative stress markers and Antioxidants status in Pulmonary Tuberculosis patients in a Nigerian Tertiary Institution

Sabiu A 1 , Dungus MM 2 , Dalili MS 3 , Sumayyah BA 4

Background: Pulmonary tuberculosis remains a major global health concern, particularly in resource-limited settings like Nigeria. Oxidative stress has been implicated in the pathogenesis and complications of various diseases, including infectious diseases such as tuberculosis. This study explored the impact of pulmonary tuberculosis infection on the antioxidant mechanisms and the resulting redox imbalance in general. The specic objective was to determine the changes in oxidative stress marker/antioxidant level by comparing the serum levels of glutathione peroxidase, vitamin C, vitamin E and malondialdehyde between PTB patients and control group. Method: A comparative cross-sectional study was conducted involving 214 pulmonary tuberculosis patients and 214 controls at AKTH. Blood samples were collected from both groups for the measurement of malondialdehyde, glutathione peroxidase, vitamins C and E. Clinical and demographic data was obtained through structured questionnaires. Results were presented as mean and standard deviation. Mean serum levels were compared using Mann Whitney u-rank test, while Spearman correlation was used to determine correlation between malondialdehyde and antioxidants. Results: Both PTB patients and the control group were largely composed of individuals between the ages of 21 and 30 years with a mean age of 34 years and 31 years respectively. The investigation demonstrated that individuals with PTB exhibited a notably higher malondialdehyde level (1201±323µmol/L, p<0.05), in comparison to the control group (433±313µmol/L). Additionally, the average serum concentrations of glutathione peroxidase, vitamin C, and vitamin E were signicantly lower in the PTB patients (glutathione peroxidase: 218.4 ± 166.6 ng/ml, vitamin C: 6.4 ± 2.5 µg/mL, and vitamin E: 8.1 ± 1.6 µg/mL) compared to the control group (glutathione peroxidase: 653.2 ± 368.6 ng/ml, vitamin C: 8.3 ± 3.8 µg/mL, and vitamin E: 12.7 ± 2.2 µg/mL). Moreover, all three antioxidants level exhibited a negative linear correlation [glutathione peroxidase r=-0.53, vitamin C r=-0.27, and vitamin E r=-0.62] with malondialdehyde. Conclusion : In conclusion, the ndings of this research showed a signicant elevation in malondialdehyde levels among PTB patients compared to the control group, indicative of heightened oxidative stress. Concurrently, PTB patients exhibited lower serum levels of glutathione peroxidase, vitamin C, and vitamin E, suggesting a compromised antioxidant defense mechanism. The observed negative linear correlations between these antioxidants and malondialdehyde emphasize their potential role in mitigating oxidative damage. These insights may contribute to our understanding of the oxidative stress dynamics in PTB and highlight the importance of comprehensive care strategies in managing the condition.

 

Keywords: Malondialdehyde; Glutathione peroxidase, Vitamin C; Vitamin E and Pulmonary tuberculosis

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ORIGINAL ARTICLE


 

Prevalence and Reasons for Contraceptive Discontinuation among Women of Reproductive Age in Urban and Rural Communities of Kano State, Nigeria

Abulfathi AA 1 , Bukar FL 1 , Abiso MA 2 , Warshu SH 3 , Wudiri ZW 1 , Bolori MT 1 , Oloyede TA 1  

Background: Contraceptive discontinuation is a signicant factor contributing to low contraceptive prevalence in low-resource settings like Nigeria and can lead to increased unintended pregnancies and challenges in child spacing or planned parenthood. Objectives: This study aimed to assess the prevalence and reasons for contraceptive discontinuation among women of reproductive age in urban and rural areas of Kano State, Nigeria. Methods: A comparative cross-sectional study was conducted, employing structured survey questionnaires. Results : Of the 605 participants, 207 in urban and 228 in rural areas had discontinued at least one contraceptive method, resulting in discontinuation rates of 68.3% and 75.5%, respectively. The difference in discontinuation was statistically signicant, with the rural counterparts having higher discontinuation rates with a p-value ≤0.05. Implanon had the highest discontinuation rates (55.1% in urban and 37.2% in rural areas), while the withdrawal method had the lowest rates (0.0% in urban and 2.5% in rural areas). The most common reasons for discontinuation were side effects (24.2% in urban and 36.1% in rural areas), distance too far (21% in urban and 5.1% in rural areas), and husband's disapproval (12.8% in urban and 16% in rural areas). Conclusion: The high prevalence of contraceptive discontinuation poses signicant risks of unplanned pregnancy and unsafe abortions, thereby increasing maternal morbidity and mortality rates of mothers and neonates in Kano State. Urgent interventions addressing the root causes are imperative to reverse this trend, and women should have proper counselling on the side effects of the contraceptive method used.

 

Keywords: Contraceptive discontinuation, Urban, Rural, Women of reproductive age, Kano

 

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ORIGINAL ARTICLE


 
 
 

The Role of Tonsillectomy in Managing Halitosis: Our Experience 

Shu'aibu L 1 , Aliyu N 1 , Abubakar MY 2 , Adamu A 1 , Dandela S. 1

Background: Halitosis is an offensive odour emanating from the mouth and can be of oral or extra-oral origin. It is a social problem affecting approximately 25% of adults. It can be subjective or objective with tonsils contributing about 3% of objective halitosis due its characteristic crypts that are capable of retaining epithelial debris and food particles that undergo anaerobic bacterial activity producing foul smelling cheese-like substance that sometimes, becomes mineralized leading to formation of tonsilloliths. Tonsillectomy is one of the treatment options in halitosis of tonsillar origin. Objectives: To evaluate the relationship between tonsils and halitosis and to determine the role of tonsillectomy in the management of halitosis. Methods: This is a 4-year retrospective review of clinical information of patients who presented to the department of Ear, Nose and Throat, Federal Teaching Hospital Katsina with diagnosis of halitosis of tonsillar origin from January 2021 to November 2024. Data on demographics, clinical features, treatment and outcome of treatment were analysed using SPSS version 25.0. Results: Out of 28 people diagnosed with halitosis of tonsillar origin, 12 (42.9%) were males and 16(57.1%) were females with 14(50%) below the age of 20 years and 14 from 21 years to 40 years. Twelve (42.9%) had moderate halitosis while 16(57.1%) suffered halitosis of severe degree with associated recurrent sore throat in 8(28.6%), recurrent sore throat and tonsilloliths in 10 (35.7%), with 10 (35.7%) having no associated symptoms. Halitosis resolved within 4 to 6 weeks of tonsillectomy in 20 (71.4%) of the patients and within 7 to 12 weeks in 6(21.4%) of the patients while 2 (7.1%) complained of persistence of symptom 12 weeks after the surgery. Conclusion : Halitosis is a common social problem that can originate from oral or extra oral sources. Tonsils are important sources of halitosis of extra oral origin and when found to be the primary source, tonsillectomy stands as an important treatment option.

Keywords: Halitosis, Tonsilloliths, Tonsillectomy, FTH Katsina.

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ORIGINAL ARTICLE


 

Clinical Prole and Outcome of Under-ve Children with Rotavirus Diarrhoea at the University of Maiduguri Teaching Hospital, Maiduguri, Nigeria

Yusuf HM, 1,2 Asheikh MM, 1,2 Imam RA, 1,2 Nkama II, 1 Farouk AG, 1,2 Mustapha MG. 1,2  

Background: Rotavirus is the most common cause of diarrhoeal disease among children under the age of ve years. It is an important cause of serious complications and death; its contribution to childhood morbidity and mortality remains very high in our setting. Objectives: This study was conducted to determine the clinical prole and outcome of under-ve children with rotavirus diarrhoea at the University of Maiduguri Teaching Hospital (UMTH). Methods: The study was hospital-based descriptive in which 351 children with acute watery diarrhoea were consecutively recruited from September 2019 to March 2021. A pretested Case Record Form (CRF) was used to capture the presenting symptoms and signs of the participants. Clinical ndings like axillary temperature, hydration status, features of dehydration and presence or absence of oedema were documented. The duration of hospital stay and clinical outcome of the subjects were also documented. Stool samples were collected from participants and tested for rotavirus using an immunochromatographic test. Data generated were analysed using IBM SPSS version 26. Results : One hundred and forty-four (41%) of the participants have rotavirus diarrhoea. Participants with rotavirus and non-rotavirus diarrhoea presented with similar clinical features. However, vomiting (χ2 =5.688, p=0.001), decline in urine volume (χ2 =7.058, p=0.006), and dehydration (χ2 =4.748, p=0.034) were found to be signicantly higher in participants with rotavirus diarrhoea compared to non-rotavirus diarrhoea. Participants with rotavirus diarrhoea are likely to have a shorter duration of hospital stay compared to participants with non-rotavirus diarrhoea (U= -2.114, p=0.034). Conclusion: The spectrum of clinical presentations were similar among participants with rotavirus diarrhoea and non-rotavirus diarrhoea. However, vomiting was more frequently seen in participants with rotavirus diarrhoea compared to nonrotavirus diarrhoea. Rotavirus infection should be suspected in under-ve children with sudden onset of acute diarrhoea and vomiting and managed accordingly in the study area.

Keywords: Rotavirus, Acute watery diarrhoea, under-ve
 

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ORIGINAL ARTICLE


 
 
 

Mental Health Effects of Social Media Use Among Undergraduate Students of the College of Medical Sciences, University of Maiduguri

Bukar FL 1 , Abulfathi AA 1 , Musami UB 2 , Bello U 1 , Kareem YA 3 , Yanga PJ 4 , Abubakar Y 4 , Dagala AV 4 , Abubakar A 4 , Chilariye KA 4 , Amodu MO 1 .

Background: Social media refers to any internet-based platform or service (such as Facebook, WhatsApp, and Twitter) that enables individuals to interact verbally and nonverbally. Evidence suggests a direct relationship between social media usage and impaired mental health, including depression, anxiety, loneliness, and narcissism . Objective : The main objective was to determine the mental health effects of social media use among undergraduate students of the College of Medical Sciences, University of Maiduguri. Methods: A descriptive cross-sectional study design was employed with a sample size of 400 students. A multistage sampling technique was utilised to select the respondents, and a self-administered questionnaire with socio-demographic questions to obtain information on demographic and social media characteristics and general health questions (GHQ-12) was used to screen for psychological distress. The data were analysed using descriptive statistics and a Chisquare test, with a level of statistical signicance set at p < 0.05 . Results: Four hundred respondents completed the questionnaire. Of these, 43.5% were aged between 21 and 25 years, with a mean age of 23.4+2.2. More than half (55.5%) were male. Most respondents (60.8%) were aware of the effects of social media on mental health. WhatsApp (63.5%) was identied as the most frequently used social media platform. It was found that (34.3%) had psychological distress. Both age and academic level were signicantly associated with mental health status. Conclusion: The study revealed a high prevalence of psychological distress, highlighting the signicant mental health challenges faced by this demographic. Therefore, students should be encouraged to promote a balanced use of these platforms.

Key words: Social Media, Mental Health, College Undergraduate, Students, University of Maiduguri

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ORIGINAL ARTICLE


 

Effectiveness of Training Workshop on Knowledge of Healthcare Providers on Breaking Bad News to Cancer Patients: A Multi- Institutional Study

Umar SS 1 , Otene SA 2 , Tijjani AA 3 , Bojude AD 4 , Sarimiye FO 5 , Abubakar SB 6 , Okwor VC 7 , Ikhile EA 8 , Suleiman AG 9 , Hamidu SK 10 , Nwordu VC 11 , Lasebikan N 12 , Ali-Gombe M 11 , Aliyu UM 13

Background: Bad news is dened as ‘any information that adversely and negatively affects the patients' view of their future'. It is one of the most critical aspect in the management of cancer patients. Many models have been developed and studies have shown that breaking bad news is most effective if it is structured following established guidelines. Despite this, healthcare workers who provide care to cancer patients receive little to no formal training in breaking bad news especially in low-resource settings Objective: The objective of the study was to train all categories of healthcare providers responsible for cancer patients (including specialist doctors, nurses, psychologists) on breaking bad news and assess effectiveness of the training on their knowledge of breaking bad news. Methods: This was a quasi-experimental study to determine the effect of a training workshop on the knowledge of healthcare providers on breaking bad news. Baseline data on socio-demographic characteristics and their knowledge on breaking bad news was assessed prior to training. This was followed by an 8- hour workshop which comprised of lecture series, practical demonstration and group tasks on breaking bad news. A post training evaluation was conducted and the results analysed using frequency, tables, charts and difference of mean tests. Results A total of 590 and 528 healthcare providers participated in the pre-test and posttests respectively. The mean age of healthcare providers was 39.2 ± 9.1 years, with 385 (64.4%) being females and 205 (35.6%) being males. The doctors, nurses and other healthcare providers constituted 210 (35.6%), 211 (35.8%) and 169 (28.6%) respectively. There was signicant improvement in knowledge of participants when the pre and post training knowledge scores were compared (p<0.0001). However, on disaggregation of participants into geopolitical zones, only the North Central (p = 0.0014), North East (p = 0.0024), South East (p = 0.03), and South West (p = 0.0079) zones recorded signicant increase in the knowledge score of participants following training. Conclusion: This study demonstrated the effectiveness of training in addressing the knowledge gaps on breaking bad news among healthcare providers of cancer patients.

Keywords: Knowledge, Breaking Bad News, Cancer, SPIKES Model

 

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CASE REPORT


 
 
 

Spontaneous Right Lower Limb Gangrene in A Neonate: A Case Report

Shamsuddeen M

Background: Gangrene is the term used to describe the death or decay of tissue due to lack of blood supply.

Spontaneous lower limb gangrene in neonates is a rare entity. Most often, the aetiology remains unidentied. Case summary: I report a case of spontaneous lower limb gangrene which developed soon after birth. No aetiology was identied. My Patient was managed with supportive care that included antibiotics and antithrombotics, and developed auto amputation at the ankle, which was refashioned to knee disarticulation.

Keywords: Spontaneous, autoamputation, lower limb, antibiotics

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CASE REPORT


  Symptomatic First- and Second-Degree Atrioventricular Block in a Young Soldier: A Diagnostic Dilemma in a Resource-Limited Setting

Galtimari IA, 1,2 Talle MA 1,2

Background: First-degree AV block and Mobitz I second-degree AV block are largely asymptomatic. However, severe prolongation of the PR interval in patients with rst-degree AV block could result in simultaneous atrial and ventricular contractions (loss of AV synchrony) and Talle MA symptoms akin to pacemaker syndrome. Case Summary: We present a 25-year-old male soldier who presented with a three-year history of exertional shortness of breath, fatigue, palpitations, and pre-syncope. Examination revealed bradycardia (42 bpm), other cardiovascular ndings were normal. ECG showed rst-degree AV block (PR interval: 347ms) with a broad QRS complex, later progressing to Mobitz I second-degree AV block (45 bpm). Exercise testing revealed an inadequate PR shortening despite an increase in heart rate. Other investigations, including echocardiography and blood tests, were normal. Limited access to Holter ECG and genetic testing hindered denitive diagnosis. Given the risk of progression to complete heart block and sudden cardiac death, early electrophysiology evaluation and pacemaker implantation are recommended.

Keywords: Symptomatic bradycardia, First-degree AV block, Mobitz I second-degree AV block

 

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bomj-vol21-issue-2

Written by Administrator. Posted in Archives pages

 
 

 

July - December 2024
Volume 21 | Issue 2 

This journal has been online since Saturday, April 05, 2013

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This Journal allows immediate access to content in HTML + PDF for both current and archived editions. 

Mobile access
Full text of the articles can be accessed via our android application and mobile site free of charge.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License

 

 

ORIGINAL ARTICLE


 
 
 

Socio-demographic Profiles and Referral Patterns of Pediatric Patients in the Emergency Department of a Tertiary Hospital, in a Resource Limited Setting

C Ani, R Ewa- Odiase, O Ekienabor

Background : Quality emergency care stands as a vital pillar within a well-functioning health system. Ensuring timely and effective care for critically ill children is paramount for positive outcomes. Although referrals for expert care are common, the absence of a profound understanding of socio-demographic characteristics and the lack of an organized referral and feedback system can significantly compromise the delivery of optimal care. Addressing these gaps is essential to uphold the standard of care and enhance the overall effectiveness of the healthcare system. Methods: This was a cross-sectional observational study design, conducted at the children emergency room (CHER) of the University of Benin Teaching Hospital, Benin-City, Edo state. All patients below the age of 18 years, who were medically referred to CHER over the period of 4 months were recruited. All the data obtained were then documented using a structured questionnaire, which contained information on the socio-demographic data and Referral Patterns. All collected data underwent thorough checks for completeness, appropriately coded, and were subjected to analysis using IBM-SPSS version 26. Results: A total of 525 patients were seen at CHER over the period of 4 months, out of which 300 (57.1%) were referred; predominantly males (64.7%). Children below the age of 6 months had the highest referrals (36.7%), while subjects whose fathers had no formal education had the lowest (2.7%) p<0.001. Medical officer cadre had the highest number of referrals (162 [54.0%], p<0.001). Most of the referral contained the presenting complaints 206 (68.7%), working diagnosis 170 (56.7%) and reason for the referral 190 (63.3%), however, less than half had details of examination findings (144, 48.0%), investigations done (94, 31.3%) and treatment offered (116, 38.7%). Very few (2.7%) of the referring health workers/ facilities requested for a feedback p<0.001. Conclusion: The socio-demographic profile and referral patterns play a pivotal role in shaping the quality of care for paediatric patients. Therefore, there is an imperative need for comprehensive education and awareness initiatives on medical referrals.

Keywords:

 

Key words: Socio-Demographic, Referral, Pattern, Tertiary

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ORIGINAL ARTICLE


 
 
 

Correlation of Maternal Serum Uric Acid and Perinatal Outcome in Hypertensive Disorders of Pregnancy

 

Kwari SD, Chama CM, Audu BM, Bako B

 

Background: Hypertension is a common medical disorder seen in pregnancy and it is responsible for signi?cant maternal and perinatal morbidity and mortality, especially in developing countries. A direct correlation has been observed between maternal serum uric acid levels and adverse fetal outcomes. An assay of uric acid may influence the foetus's delivery timing to avoid further intrauterine complications. Objectives: To determine the relationship between maternal serum uric acid level and perinatal outcomes in women with hypertensive disorders in pregnancy and normotensive pregnant women and to determine the critical value of serum uric acid for the occurrence of adverse perinatal outcomes in women with hypertensive disorders in pregnancy. Method: This was a hospital-based cross-sectional study in the Department of Obstetrics and Gynaecology, University of Maiduguri Teaching Hospital (UMTH), Maiduguri, Nigeria, from 1st December 2010 to 30th April 2011. Patients were recruited consecutively as they were admitted into the labour ward with a hypertensive disorder in pregnancy. Socio-demographic variables, clinical characteristics, and perinatal outcomes were obtained. An assay of maternal serum uric acid and degree of proteinuria were carried out and recorded on a predesigned proforma. Results: The majority of the hypertensive group were unbooked 119(74.4%) and had no formal education 85(53.1%). Twenty-two-point-?ve percent 36(22.5%) of the hypertensive group were delivered by caesarean section compared to 33(10.3%) of the normotensive group, P 0.008. The hypertensive group delivered earlier (37.1±2.2weeks vs 38.6±0.9) and their babies weighed less (2.45±0.7 vs 3.15±0.5kg) (P <0.001). Hyperuricaemia was significantly associated with adverse perinatal outcomes such as prematurity (P <0.001), low birth weight (P <0.001), intrauterine growth restriction (P <0.001) foetal distress (P <0.001), and early neonatal death (P <0.001). The critical value of maternal serum uric acid was 455umol/l and it was signi?cantly associated with low birth weight (P <0.001), intrauterine growth restriction (P <0.001), intrauterine fetal death (P 0.001) and admission to special care baby unit (P 0.017), among the hypertensive group after regression analysis for confounders. Conclusion: Elevated maternal serum uric acid level is signi?cantly associated with poor perinatal outcomes in women with hypertensive disorders in pregnancy and a critical value of 455umol/l can be used to time delivery and avert adverse perinatal outcomes. 

Keywords: Correlation, Hypertensive disorders in pregnancy, maternal serum uric acid, perinatal outcome

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ORIGINAL ARTICLE


 

Value of Ultrasonography in Diagnosis of Acute Appendicitis: A Cross Sectional Prospective Study

 

Obirija SE[1], Rasheed MW2,3, Eze KC4, Orji MO5, Eni UE6, Okonkwo JE7, Oji CC8, Muhammed MF9

 

Background: Abdominal ultrasonography is an essential imaging modality in diagnosing patients with acute appendicitis. Its major advantages include high diagnostic accuracy, availability, affordability, and excellent safety pro?le relative to other imaging modalities with few limitations in children. Clinical diagnosis of acute appendicitis and the modi?ed Alvarado scoring system (MASS) have good sensitivity, but low speci?city. Methods:  This was a prospective comparative study at Federal Teaching Hospital, Abakaliki which lasted for 1 year and eight months from April 2018 to December 2019 which involved 50 patients with clinical presentations of acute appendicitis who were evaluated clinically using the MASS and by ultrasonography before surgical treatment and ?nal diagnosis with histology. The following were recorded for data analyses:  socio-demographic data, clinical features and laboratory ?ndings (modified Alvarado Score), ultrasonographic score, clinical diagnosis, and ?nal (histological) diagnosis. The data were analyzed using a statistical package for social sciences for Windows version 22 (IBM, USA, 2015). Results: The age of the participants ranged from 4-70 years with a mean age of 31.5±17.2 years. The majority of the participants, 39 (78%) patients were within 31-40 years. The gender distribution showed that more males-29 (58%) than females-21 (42%) participated in the study. The sensitivity, speci?city, and diagnostic accuracy of ultrasonography were 95.5%, 83.3%, and 94% respectively which were signi?cantly better than the corresponding indices of modi?ed Alvarado score: 86.4%, 44.4%, and 84% respectively. The optimum (cut-off) ultrasonographic score of 3.75 yielded sensitivity and speci?city of 95.5% and 100% respectively.   Combined ultrasonographic and modi?ed Alvarado score of 11.75 (optimum score) yielded a sensitivity of 84.1% and a speci?city of 100% in diagnosing acute appendicitis. Conclusion: Ultrasonography has a high diagnostic yield in the evaluation of acute appendicitis and should be adopted as the modality of choice in our environment. Ultrasonographic scoring system improved the diagnostic yields of ultrasonography and should be incorporated as a tool in the ultrasonographic evaluation of patients with acute appendicitis. More importantly, the surgical specimens should be submitted for a de?nitive histopathology examination. 

 

Keywords: Ultrasonography, Diagnostic accuracy, Acute appendicitis

 

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ORIGINAL ARTICLE


 
 
 

Burden, Associated Factors and Outcome of Jaundice among Babies seen at a Tertiary Hospital in Northern Nigeria. 

 

Musa AZ1, Mustapha SS1, Adamu SA1, Bawa IA2, Abdussalam ML3 

 

BackgroundJaundice is the yellowish discolouration of the skin and sclera resulting from the deposition of excess bilirubin (hyperbilirubinaemia) on the skin and mucous membranes. Most cases of neonatal jaundice are self-limiting with an excellent prognosis but in some cases complications can ensue. Bilirubin encephalopathy is an uncommon but devastating complication of severe hyperbilirubinaemia which if untreated can lead to kernicterus with eventual risk of death or long-term neurodevelopmental impairments. The aim of this study was to assess the prevalence, associated factors and outcome of neonatal jaundice in Special Care Baby Unit of a tertiary hospital in Bauchi, Nigeria. Methods: This retrospective descriptive study was conducted over a one- year period. Information captured included sociodemographic variables, maternal obstetric history, and physical ?ndings of babies. Jaundice was assessed both clinically using visual assessment as the yellowish discolouration of sclera and mucous membranes and laboratory assessment using Selectra ProS chemistry analyser.  Data was analyzed using SPSS version 20; both descriptive and inferential statistics were used where appropriate. Results: One hundred and twenty (16%) out of 748 babies admitted were diagnosed with jaundice during the study period. Of these, 65 (54.2%) were males and 55 (45.8%) were females giving a M: F ratio of 1.2:1. Majority of the babies developed jaundiced within the first 72 hours of life. Sepsis (72.5%), ABO Incompatibility (25.8%) and prematurity (22.5%) were the leading causes of neonatal jaundice. All babies had phototherapy (100%) while only 29 (24.2%) of them had EBT. The number of patients with BIND score of 4-6 (10.8%) and 7-9 (10.0%) were similar. A majority of the patients (81%) were discharged, eight (6.7%) were discharged against medical advice (DAMA) and 14 (11.7%) cases resulted in mortality. Conclusion: Neonatal jaundice is a common cause of morbidity and mortality in our environment, predominantly affecting males. Sepsis is identi?ed as a signi?cant causative factor. Effective management and early intervention are crucial in reducing the burden of this condition. 

 

Keywords: Neonatal jaundice, Male, Sepsis, Outcome 

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 

Depression, Anxiety and Stress levels among Optometry Students in the University of Benin Nigeria

 

Ebeigbe J.A, Okungbowa N.E, Obahiagbon E.A and Okoro C.C

 

Background: Several studies have shown that University students experience high levels of mental health problems such as stress, anxiety and depression. The universal and increasingly competitive nature of higher education can exacerbate common academic stressors which contribute to mental health issues among University students. Objective: This study assessed the prevalence and possible correlates of depression, anxiety and stress among students in the Department of Optometry, University of Benin. Method: This cross-sectional descriptive study was conducted among 383 undergraduates. A convenience sample of Optometry students were interviewed using a questionnaire to record their socio-demographic data and their responses to the 21question version of the Depression, Anxiety Stress Scale (DASS 21) questionnaire. The female respondents made up 57.4% (220) of the sample population. Age range for the sample was 18 to 33 years with a mean age of 25.48 (6±2.1 SD) years. Results: Prevalence of depression (40.2%), anxiety (51.2%) and stress (35.5%) of varying degrees was recorded. There was no signi?cant difference in depression, anxiety or stress between genders (p>0.05). Living arrangements, academic performance, having to repeat a class, parents’ marital status and family economic situation had positive association with depression, anxiety and stress. Statistical differences across these parameters were signi?cant p<0.05. Conclusion: Results could be helpful in designing strategies for the early identi?cation of mental health disorders, as well as psychological and other interventions that promote mental health and wellbeing among university students. 

 

Keywords: Depression, anxiety, stress, mental health, students

 

[FULL ARTICLE (PDF)]

 

ORIGINAL ARTICLE


 
 
 

Awareness and Knowledge of Cervical Cancer Screening with the Pap Smear among Women Vising Gynaecological Clinic at the University of Benin Teaching Hospital

 

Osazee K1, Ogwah CE2

 

BackgroundCervical cancer is the most common genital tract malignancy in developing countries. It is one of the few preventable human cancers based on screening, early diagnosis, and treatment of its precancerous lesions. Screening modalities include the Papanicolaouu test (Pap Test), the High-risk Human Papillomavirus (HPV) test, and visual inspection with acetic acid and Lugol iodine. Awareness, Knowledge, and uptake of these various modalities are still poor in our environment. Methods: It is a sectional analytical study of women who visited the gynaecological clinic of the University of Benin Teaching Hospital, Benin City. This study aimed to determine the factors associated with awareness and Knowledge of cervical cancer screening with the use of Pap smear. The sample size was determined using the Leslie Kish formula, and 230 participants were recruited for the study. A self-administered structured questionnaire was used to obtain information from the participants. The data were presented in tables and pie charts and analysed using the Statistical Package for Social Science (SPSS) version 22. The associated factors were tested using the Chi-Square, and Fischer exerts, and p values <0.05 were considered signi?cant. Results: Out of the 230 respondents, 70% were aware of cervical cancer, but only 43.9% were aware of Pap smear; of the 43.9%, only 19.8% had good Knowledge of Pap smear. The majority of the respondents had their information from health workers. Level of education, marital status and parity were signi?cantly associated with awareness of Pap smear (p < 0.001). However, no sociodemographic factor was signi?cantly associated with Knowledge of Pap smear in the study. Conclusion: Awareness and Knowledge of Pap smears is still suboptimal in our environment. Education of the girl child and appropriate dissemination of accurate health information via health staff, mass media, and religious and traditional institutions will help to improve awareness and Knowledge of and acceptance of Pap smear screening tests.   

 

Keywords: Cervical cancer, Pap Smear, Screening, Awareness, Knowledge

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 

Pattern of Pap Smear Results among Postnatal Clinic Attendees in Aminu  Kano Teaching Hospital Kano: 2 Years Review.

 

SA Gaya1, ZD Ahmed1, S Mukhtar2

 

BackgroundCancer of the cervix is second to the cancer of the breast and the two were responsible for three in ten of the cancers diagnosed in both sexes combined in 2020 in sub–Saharan Africa.  The risk of a woman in subSaharan Africa developing cervical cancer is 3·5%. Cervical cancer is preventable with early detection and increased postpartum uptake may aid its early detection. Method: It was a retrospective cross-sectional study that involved women in the puerperal period who attended Post post-natal clinic at the Department of Obstetrics and Gynecology, AKT.H. between January 2020 to January 2021. Data was obtained with a proforma, analysed using SPSS version 23.  Results were presented in tables, and summarized in terms of mean and standard deviation as well as frequency and percentages. A test of association was done using chi-square statistics. Results: Out of the 504 postpartum patients who had Pap smears, only 64% of the folders were available for analysis. The mean age was 36.7±6.4 and most of the respondents were multiparous 275 (84.9%). Majority of the women were married 322 (99.4%), 45.4% had secondary education as their highest level of education and 32.7% had tertiary education. The result of the Pap smear cytology was abnormal in 2.1% and LSIL is the commonest abnormality 5 (1.5%) Conclusion: The uptake rate of Pap smears was low (11.8%), and abnormal pap smears accounted for 2.1%. Pap smear abnormalities were commonest among those aged 19 to 39 years and those who were multiparous. 

 

Keywords: Pap smear, Post natal clinic 

 

[FULL ARTICLE (PDF)]

 

ORIGINAL ARTICLE


 
 
 

Abruptio Placentae: Incidence and Pregnancy Outcome in Abubakar Tafawa Balewa Teaching Hospital, Bauchi: A 5-Year Review. 

 

Palmer OH, Dattijo LM, Oranuka KP, Adeleke OP, Musa, AD, Aminu BM 

 

BackgroundAntepartum hemorrhage especially abruptio placentae remains one of the leading causes of materno-foetal morbidity and mortality globally, more especially in middle and low-income countries like Nigeria. It is one of the common causes of foetal loss and severe maternal morbidity at Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), Bauchi. This study seeks to determine the incidence, common risk factors and foeto-maternal outcomes in ATBUTH, Bauchi. Objectives: To determine the incidence, common risk factors, and foeto-maternal outcomes of pregnancies complicated by abruptio placentae in (ATBUTH) Bauchi. Study design: This was a retrospective study of cases with abruptio placentae that presented to ATBUTH, Bauchi over 5 years between 1st January 2015 and 31st December 2020. Results: The incidence of abruptio placentae in this study was 0.93% with an age distribution of 17-47 years and a mean maternal age of 28.5 years. Majority of the patients were multi-gravida, unbooked, and married. More than half of the patients had no formal education. Risk factors identi?ed were hypertension in 86 (50.6%) of cases, previous history of abruptio placentae in 73 (42.9%), and multiparity in 144 (84.7%) of cases. Clinical features were similar to those of other studies. Complications observed in this study included maternal shock, post-partum haemorrhage, and maternal death. Foetal complications included premature deliveries, intra-uterine fetal death (IUFD), and a high perinatal death of 103 (60.6%). Conclusion: Abruptio placentae is common in Bauchi and is a leading cause of both maternal and fetal morbidity and mortality. 

 

Keywords: Antepartum hemorrhage, abruptio placentae, foeto-maternal outcome. 

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 

Clinical Staff’s Perception and Practice of Point-Of-Care Testing of Acutely-III Children and Adolescents at a Referral Hospital in Southern Nigeria 

 

Abiodun MT1, Ayinbuomwan E2 

 

Background: Point-of-care tests (POCTs) can shorten the time taken to arrive at de?nitive diagnoses in many paediatric illnesses including surgical disorders. Therefore, POCT is a veritable tool in the investigation and management of acutely-ill children in emergency departments (EDs). Objective: To evaluate the perception, practice and determinants of point-of-care testing by clinical staff attending to acutely-ill children and adolescents in our centre. Methods: This study adopted a cross-sectional design. Data were collected with a semi-structured questionnaire. Participants’ overall perception of POCT adequacy was assessed on a 100mm uncalibrated visual analogue scale (VAS). Frequency of POCT device usage and actual point-of-care testing in the preceding 24 hours were documented. Inferential analysis assessed factors in?uencing participants’ perception. P-value < 0.05 was considered signi?cant. Results: Altogether, 134 healthcare workers participated in the study; they were mainly from the Children Emergency Room 39 (29.1%), Medical Emergency department 30 (22.4%) and Surgical Emergency department 22 (16.4%). Their mean (SD) age was 33.2 (6.3) years. A majority 98 (85.2%) of them agreed that POCT shortens the time-to-diagnoses in their patients. POCTs recently used in the EDs were pulse oximeter 91 (67.9%), glucometer 85 (63.4%), urinalysis 52 (38.8%) and malaria rapid diagnosis test (mRDT) 43 (32,1%). Professional cadre signi?cantly in?uenced POCT perception and usage (p=0.02). Participants’ overall VAS score on POCT adequacy in the EDs was satisfactory (63.0±24.4) and similar in both gender (t =1.780; p= 0.078). Conclusion: Point-of-care testing is favourably perceived and practiced in the evaluation of acutely-ill children and adolescents. There is a need to improve the availability of POCTs in paediatric acute care setting.   

 

Keywords: Point-of-care testing, perception, practice, clinical staff, children, emergency 

 

[FULL ARTICLE (PDF)]

 

ORIGINAL ARTICLE


 
 
 

Clinico-Pathological Analysis of Ovarian Cancer in a Tertiary Hospital in North-East Nigeria: A 10-Year Review 

 

Kabir A,1 Dahiru A M,2 Farouk H U,3 Bukar A Z,1 Lawan A I,4 Abdullahi Y M

 

Background: Cancer of the ovary being the second most common gynecological malignancy in Nigeria and most countries in the world, is a major cause of morbidity and mortality. The aim of this study is to determine the frequency of ovarian cancers and analyse their clinico-pathological characteristics at a tertiary health institution in Gombe. Methods: This study was a retrospective review of all cases of histologically con?rmed ovarian cancers at the Department of Histopathology, Federal Teaching Hospital Gombe over a period of 10 years. Relevant information was extracted from the histology request forms and patients’ medical case records. Data were analysed statistically using SPSS Version 20.0 and results were presented in tables and charts. Results: One hundred and seven (107) cases of ovarian cancer were diagnosed, which constituted 14.7% of gynaecological malignancies (730) and 2.7% of total cancers (3993). Patients were aged between 11 and 80 years. The modal age group was 31–40 years. The three most common clinical presentations included abdominal distension, abdominal pain and weight loss; while the commonest stage at presentation was stage III. Surface epithelialstromal cancers were the most common histological class, with high-grade serous carcinoma being the most common histological variant. The most common treatment modality was surgery and chemotherapy. Conclusion: This study shows a predominance of ovarian cancer cases in younger, reproductive women, and at advanced stage of presentation. Similarly, the preponderance of high-grade serous carcinoma in this female population is a major health concern and demands proactive measures to address it. 

 

Keywords: Ovary, Cancer, Clinical features, Histological types 

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 

Neuroimaging Patterns of Stroke in Adult Patients in North-Eastern Nigeria 

 

Umar UH1, Farate A1, Yunusa DM2, Lawan MM1, Goni MA1, Ahmadu MS1, Ahidjo A

 

Background: Stroke is a major cause of morbidity and mortality worldwide and is worsening in sub-Saharan Africa. Neuroimaging plays a vital role in its con?rmation and ruling out stroke mimics. Brain CT scan is the workhorse in the management of patients with acute stroke where time matters. Method: This was a retrospective cross-sectional study of patients with clinical stroke and con?rmed on CT scans from January 2020 to December 2023 that were conducted at departments of Radiology, University of Maiduguri Teaching Hospital and State Specialist Hospital, Maiduguri, North-eastern Nigeria. Data were retrieved and recorded from the archives which included biodata and CT scan patterns (stroke subtype and site, vascular territory, and number of lesions).  Data were analyzed using Statistical Package for Social Sciences version 26 (IBM, 2019, Illinois, USA). Results: A total of 328 patients of the study population were recorded, of which 187 patients 

(57%) were males and 141 (43%) were females. The age ranged from 20 - 98 years, with a mean age (± SD) of 59.1 ± 14.9 years and a male-to-female ratio of 1.3:1 and the majority of the patients (55%) were aged = 60 years. Ischaemic stroke was seen in 245 patients (75%) and haemorrhagic stroke (HS) was seen in 83 patients (25%). The most frequent stroke subtype was ischaemic stroke in both male and female patients. The relationship between the stroke subtype and age group was statistically signi?cant (p=0.0001). Ischaemic stroke was the most observed subtype in all age groups than HS. Lobar location in particular the parietal lobe was the most commonly involved site in this study. The commonest vascular territory was the middle cerebral artery and the majority of stroke cases (88%) were solitary lesions. Conclusion: Neuroimaging differentiates infarction from haemorrhage and guides the treatment of acute stroke patients. Ischaemic stroke was the most frequent subtype in all genders and age groups with lobar location accounting for most stroke sites in this study. Noncontrast brain CT scan is the ideal imaging modality in the management of acute stroke. 

 

Keywords: Stroke, Brain CT, Subtype, Site, Vascular Territory 

 

[FULL ARTICLE (PDF)]

 

ORIGINAL ARTICLE


 
 
 

Cryptosporidiosis in Human Immunode?ciency Virus Positive Patients and Associated Risk Factors in Maiduguri, Northeastern, Nigeria 

 

MK Usman1, AS Baba2, KB Ali2, YM Yakubu3, BB Daggash3, AB Shettima3, NG Zango3, DI Mohammed 3, AA Abdullahi4, Y Mohammed5, GB Gadzama2, SB Zailani3 

 

Background: Cryptosporidium is an intestinal parasite that causes diarrhoea in immune-compromised individuals. It is associated with high morbidity and potentially high mortality rates among the immune-compromised, resulting in serious economic threats. This study aims to evaluate the prevalence and risk factors of Cryptosporidiosis among people living with HIV (PLWH) in Maiduguri, Nigeria. Methods: This cross-sectional study was conducted at the Microbiology Department, University of Maiduguri Teaching Hospital, Nigeria. Non-probability consecutive sampling technique was used, and a total of 269 stool samples were collected from in and outpatients attending the antiretroviral (ARV) clinic in UMTH. Each sample was collected according to standard protocol. Cryptosporidium species were detected and identi?ed using Modi?ed Ziehl-Neelsen (MZN) staining, and polymerase chain reaction–restricted fragment length polymorphism (PCR-RFLP) of the small subunit (SSU) rRNA genes. Risk factors predisposing to Cryptosporidiosis were also assessed and the relationship was statistically determined. Results: Among the 269 enrolled patients, the prevalence of Cryptosporidiosis was 13.4% using Modi?ed ZhielNelseen stain (MZN), 17.1% using enzymes linked immunosorbent assay (ELISA), and 19.3% using polymerase chain reaction (PCR). Cryptosporidiosis was found to be statistically associated with Cluster of Differentiation 4 (CD4) count <200 cells/mm3, male gender, poor toilet facility, and low personal income. Conclusion: Cryptosporidium is a common cause of diarrhea among people living with HIV in Maiduguri. 

 

Keywords: Cryptosporidium, Maiduguri, HIV 

[FULL ARTICLE (PDF)]

CASE REPORT


 

Diagnosis and Management of Acute Pulmonary Thromboembolism Complicating Acute Myocardial Infarction in a Resource Poor Setting: A Case Report 

 

Baba MM1, Musa MS2, Mohammad IH3

 

Background: Pulmonary thromboembolism is a life-threatening medical emergency occurring as a result of sudden occlusion of the pulmonary artery or its branches by a thrombus originating from the right heart or the deep veins. Case Summary: The patient is a 55-year-old lady with poor financial background developed sudden onset of breathlessness, cough with haemoptysis associated with chest pain while on admission for biventricular heart failure secondary to myocardial infarction. No previous history of deep venous thrombosis, pulmonary embolism or recent surgery. However, she was bedridden at home for two months prior to the hospitalisation. Wells clinical score was 7 with high-risk strati?cation,  computerised tomography pulmonary angiography confirmed the diagnosis of pulmonary thromboembolism. Unfractionated heparin and Apixaban were used in the treatment of pulmonary thromboembolism in this patient. Conclusion: Diagnosis and management of pulmonary thromboembolism posed a signi?cant challenges in a resource poor setting, therefore high index of suspicion, timely assessment for the likelihood of PTE and prompt risk stratification are crucial. While thrombolytic therapy is the recommended treatment option for high risk patient, however the use of unfractionated heparin is an alternative. 

Keywords: Pulmonary thromboembolism, Myocardial infarction, Heart failure. Resource poor setting

 

[FULL ARTICLE (PDF)]

 
 
 
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BOMJ Vol21 Issue 1

Written by Administrator. Posted in Archives pages

 
 

 

January - June 2024
Volume 21 | Issue 1

This journal has been online since Saturday, April 05, 2013

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SHORT COMMUNICATION


 
 
  Assessment of Community Participation in Ward Development Committee as A Vehicle for Inclusion in Community Programmes in North-West Nigeria: A Cross-Sectional Study

Sulaiman H., Gadzama D.A., Jibril M.B.

Background: Community participation is a process where community members come together to identify and plan how to solve their needs. It is thought that community participation in primary health care will result in more accessible, relevant, and acceptable services which will in turn result in better health outcomes and patient satisfaction. This study sought to determine the level of community participation in Ward Development Committee from the perspectives of the committee members, Healthcare workers and community members. Objective: to evaluate the extent of Ward Development Committees' (WDCs) involvement in community-based initiatives and projects. Methods: The study was a descriptive cross-sectional study, conducted in Kudan Local Government Area of Kaduna State, Nigeria. All HCWs who had been in service for at least 6 months and WDC members who had served on the committee for at least 6 months were involved in the study. A multistage sampling technique was used to select the respondents from the community. Data was collected using a semi- structured interviewer-administered questionnaire developed by the researchers. The level of community participation was assessed by adapting Rifkin’s model for assessing community participation which has 5 indicators; needs assessment, organization, resource mobilization, leadership, and management. Results: From the perspective of the healthcare workers, ward development committee and community members, the level of community participation was 5 in organization and 4 in Leadership, Resource mobilization and Management, respectively. This indicates wide participation. The level of community participation is 3 in Needs Assessment from the perspective of healthcare workers and Ward Development Committee members and 1 for community members indicating moderate and narrow community participation. Conclusion: While community participation in Kudan’s WDC activities is commendable, there is potential for enhancement. We recommend that the government develops a policy on community engagement to ensure comprehensive community participation in all health-related projects.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

Computed Tomographic Evaluation of Patients with Sinonasal Diseases in Maiduguri, North-Eastern Nigeria

Umar UH, Adamu A, Yunusa DM, Farate A, Lawan MM, Ahmadu MS, Ahidjo A, Mustapha Z

Background: Paranasal sinuses (PNS) are air-filled spaces which surround the nasal cavity. Sinonasal diseases (SNDs) are various pathologies ranging from inflammatory to benign and malignant neoplasms of the PNS and nasal cavity. Rhinosinusitis (RS) is the most frequent SND and its prevalence in the general population is relatively high, worldwide. Objective: To evaluate the computed tomographic findings of patients with SNDs in Maiduguri, North-eastern Nigeria. Methods: This was a retrospective study on CT scans of patients with SNDs who were referred to the Department of Radiology, Federal Neuro-psychiatric Hospital Maiduguri and State Specialist Hospital Maiduguri for computed tomography (CT) scans of PNS from January 2019 to December 2022. Data were retrieved and recorded from archives of the Departments which include age, sex, clinical presentations and CT findings. Data were analysed using IBM SPSS version 23. Results: The CT scans of one hundred and forty-six patients were reviewed; the majority of them being adolescents and young adults, with a mean age of 34.6 ± 16.1 years and a male-to-female ratio of 1.8:1. The commonest clinical presentation was nasal obstruction and inflammatory SNDs were the most frequent subgroup of aetiology. Mucosal thickening was the most frequent CT finding, and the most common CT diagnosis was RS. The maxillary sinus was the site that was mostly involved. Also, the lesions of SNDs were mostly multiple and bilateral. Conclusion: SNDs are common health conditions and the findings in this study showed that CT was a useful diagnostic tool. CT also helped to establish the extent of disease making it easier for preoperative preparation in case of surgical intervention. Rhinosinusitis was the most common inflammatory SND in this study.


Keywords: Computed tomography, Paranasal sinus, Sinonasal disease, Inflammatory, Rhinosinusitis, Polyposis

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

Sonographic Evaluation of Renal Volume in Type 2 Diabetes Mellitus

Umweni A.A, Otaren N.J.

Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD) worldwide and it is estimated that more than 20% of type 2 diabetic patients may develop ESRD during their lifetime. methods: The study is a prospective ultrasonographic evaluation of kidney volumes in 228 adults with type 2 diabetes and 228 normal non-diabetic adult controls carried out at Aminu Kano Teaching Hospital, Nigeria from June 2015 to May 2016. The data were analysed using computer-based SPSS version 23 software for Windows. Results: The 228 patients with type 2 diabetes studied were composed of 120 (53%) females and 108 (47%) males with a mean age of 47.7years, (range 29– 67 years), while the 228 normal control group were composed of 108 (47%) females and 120 (53%) males with a mean age of 46.9 years, (range 28- 69years). The age difference between the study and control groups was not statistically significant (p=0.43). The mean renal volumes were significantly higher in the study group (114.10+3.97ml) compared to the control group (95.34+2.59ml); this was statistically significant (p=0.001). The mean renal volumes were higher in males compared to the females in both the study group and the control (p=0.001). The left mean renal volumes were higher than that of the right in both the study and the control groups (p=0.001). There was, however, no significant correlation between renal volume and BMI (p=0.086). Conclusion: The mean renal volume is significantly higher among diabetics compared with normal controls. Patients with Type 2 diabetes mellitus have no significant correlation between renal volume and BMI.


Keywords: Type 2 diabetes Mellitus, BMI, renal volume.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

The Outcome of Teenage Pregnancies in A Tertiary Health Facility in Maiduguri Nigeria: A Retrospective Case-Control Study

Kwari SD, Chama CM, Mairiga AG

Background: Teenage pregnancy is becoming one of the most important social and public health problems worldwide, with a varying prevalence rate. It is associated with adverse maternal and fetal outcomes. Objective: To determine the maternal and fetal outcomes of teenage pregnancy at a tertiary care hospital. Method: A retrospective case-control review of all teenage pregnancies seen at the University of Maiduguri Teaching Hospital over ten years was carried out. The outcome was analysed and compared with that of older mothers who served as controls. Result: Teenage pregnancies accounted for 7.3% (n =1558) of the 21,310 deliveries within the study period. The mean age was 18.1 years. The majority of the teenagers were nulliparous (80.3%) and had no formal education (54.8%). Pregnancy-induced hypertension (22.9 % vs. 7.5% P<0.0001), preeclampsia (5.0% vs. 1.8% P0.001), eclampsia (9.7% vs. 3.6%, P<0.0001), malaria (19.0% vs. 6.4% P<0.0001), anaemia (16.5% vs. 11.5% P<0.0001), blood transfusion (7.5% vs. 1.8% P0.001), urinary tract infection (11.8% vs. 1.1%, P<0.0001), and duration of hospital stay (3.52 vs. 2.42 P0.003) were significantly higher in teenage mothers. Similarly, preterm delivery (21.1% vs 6.4% P <0.0001), low birth weight (22.2% vs. 6.1% P<0.0001), birth asphyxia (6.1% vs. 3.6% P 0.0001), and stillbirth (6.8% vs. 3.6% P 0.001) rates were higher in the teenage group. Teenagers were also more likely to be delivered by caesarean section (18.3% vs. 10.7% P <0.0001) and to have instrumental deliveries (5.0% vs 1.4% P< 0.0001). Conclusion: pregnancy among teenagers is associated with poorer maternal and fetal outcomes compared with older mothers.


Keywords: teenage pregnancy, maternal outcome, fetal outcome, tertiary care setting

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

Urinary Tract Infection Associated Co-Morbidities in Febrile Children in Maiduguri

Asheikh MM, Yusuf HM, Garba MA, Farouk AG, Abatcha MB, Mustapha MG

Background: Background: Fever is a common symptom in children and urinary tract infection (UTI) is one of the most common causes of fever in children. This study evaluated the co-morbidities associated with UTI in febrile children at the University of Maiduguri Teaching Hospital. Methods: Proforma detailing the history, physical examination and clinical diagnosis of the subjects were lled for all the 200 children aged 2 months to 15 years who were consecutively recruited. Urine samples were collected from each of the subjects for dip-stick urinalysis as well as microscopy, culture, and sensitivity. Data was analysed using IBM SPSS version 25. Results: Thirtynine subjects had UTI giving a prevalence of 19.5%. The common symptoms in the subjects with UTI were poor appetite and vomiting. Genito-urinary symptoms were not common among the children studied. Co-morbidities associated with UTI were malaria, (OR = 2.808; 95%CI = 1.243 – 6.346; p = 0.013), acute respiratory tract infection (OR = 0.324; 95%CI = 0.073 – 1.439; p = 0.139) and enteric fever (OR = 1.382; 95%CI = 0.544 – 3.515; p = 0.497), with malaria being the most common co-morbidity. Conclusion: Co-morbidities in children presenting with fever are common, especially in developing countries and the occurrence of UTI in the absence of genito-urinary symptoms in febrile children is not uncommon. Recommendations: Clinicians managing febrile children should have a high index of suspicion for UTI even in the absence of genito-urinary symptoms and evaluate the children for co-morbidities, for appropriate management..


Keywords: urinary tract infection, co-morbidity, fever, children, Maiduguri.

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

 Predictors of Knowledge, Attitude and Practice of Premarital Screening Among the Attendees of General-Out Patient Bauchi State Specialist Hospital, Nigeria

Musa A, Abba U, Ahmad A, Muhammad KG, Nehemiah BV, Jibril MB Ibrahim AM

Background: Premarital screening remains the only realistic approach to reduce the burden of genetic diseases such as sickle cell disease and other sexually transmitted diseases like HIV and Hepatitis B which remain a serious public health concern. The study was conducted among GOPD attendees of Bauchi State Specialist Hospital to assess their knowledge, attitude and practice of premarital screening and to find a way of increasing the awareness to the general public. Methods: A descriptive cross-sectional study was employed using a semi- structured interviewer-administered questionnaire to 331 respondents among GOPD attendees of Bauchi State Specialist Hospital. The data was analyzed using SPSS version 22.0 and level of significance was set at 0.05. Results: The mean ±SD age of the respondents was 32.2 ±11.9 and 70.7% of the respondents have good knowledge, 73.1% positive attitude and 74.3% good practice of premarital screening. Formal levels of education, age, religion, tribe, gender, occupation and marital status were the factors associated with the knowledge, attitude and practice of the premarital screening among the GOPD attendees: levels of education, gender, age and occupation for knowledge, levels of education for attitude and age for practice; remained independent predictors of knowledge, attitude and practice of the premarital screening among the GOPD attendees. Conclusion: This study shows that there is good knowledge and attitude of Premarital Screening among the study participants. However, the practice is relatively poor when compared to the other two variables. Government should sustain the awareness campaign by engaging the stakeholders, media, non-governmental organizations, religious bodies, hospitals and schools.


Keywords: Knowledge, attitude, practice, premarital screening, Bauchi

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLE


 
 
 

  Spectrum of Non-Emergency Neurosurgical Conditions in Maiduguri

Daibu U, Usman B, Mohammed B

Background: Neurosurgical conditions are fairly common in our facility. They present to the emergency unit and trauma centre in an emergency state, and otherwise to the outpatient clinic of our facility. Our facility has three (3) neurosurgeons, addressing the growing burden of neurosurgical conditions. There is little information on the pattern of presentations of these non-emergency neurosurgical conditions to the outpatient clinic in our centre. Objective: To determine the pattern of presentations of non-emergency neurosurgical conditions at our facility's outpatient clinic. Patients and Methods: A prospective observational study that recruited all patients with non-emergency neurosurgical conditions who presented to the outpatient neurosurgical clinic of the University of Maiduguri Teaching Hospital from February 2023 to January 2024. Data was analyzed using a statistical package for social sciences (SPSS) version 26. Results: A total of 139 patients were recruited during the study period. The majority (67.6%) were males with a male-to-female ratio of 2.1:1. The most common age range at presentation was 17-45 years (37.4%) with a mean age of 37years ± 20.104 SD. Back pain (25.9%) from lumbar spondylosis was the most common clinical symptom, followed by weakness of the limbs (13.6%). Forty-six-point seven percent (65 patients) presented with cranial pathologies, while 49.7% (69 patients) presented with spinal pathologies. Spondylosis (27.3%) and hydrocephalus (9.4%) were the most common diagnoses at presentation in adults and children, respectively. Majority (62.6%) of the patients required surgical intervention at the time of presentation. Conclusion: Lumbar spondylosis and hydrocephalus are our facility's most common indications for outpatient neurosurgical consultations.


Keywords: Neurosurgical conditions, Outpatient clinic, Spectrum, Presentations, Maiduguri

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ORIGINAL ARTICLE


 
 
 

  Healthcare Workers Perception and Satisfaction with the Use of Electronic Medical Records in a Tertiary Hospital in Southwest Nigeria

Azees A. S, Adebisi O. I, Olubodun T, Adeniyi M. A

Background: Adequate medical record-keeping and prompt information retrieval for decision-making are essential to effectively and efficiently run healthcare services. This process is being revolutionized with the introduction of Electronic Medical Recording (EMR) in the healthcare industry. Objectives: The study aims to assess healthcare workers' perception and satisfaction levels with the use of EMR. Methods: The study was a hospital-based cross-sectional study involving health workers as the study population. A total of 316 participants participated in the study. Respondents were selected using a systematic random sampling technique. Data was collected using a validated self-administered questionnaire and analysed using IBM SPSS version 25. Results: The mean age of the respondents was 35.7 ± 8.7 years, and the majority 41.1% were aged between 30 and 39 years. Most of the respondents 86.4%, had a positive perception of using EMR. 85.1% agreed that EMR is easy to learn, 81.0% agreed it is easy to use, 92.7% agreed that information in EMR is useful for patient care, and 78.2% agreed it improves ease of work. Respondents recommended that the EMR interphase should be more user- friendly, improving internet access, regular system updates, providing more hardware and periodic training. Conclusion: This study reported high satisfaction levels and positive perception of the EMR. EMR made work more efficient and was easy to use. Findings from this study support the adoption of EMR in tertiary health facilities.
Keywords: Healthcare workers, Perception, Satisfaction, Electronic medical records, Tertiary hospital

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ORIGINAL ARTICLE


 
 
 

  Prevalence of Primary Hyperparathyroidism and Vitamin D Status Among Urinary Tract Stone Formers in Maiduguri, Nigeria.

Mshelia DS, Gali RM, Dogo HM, Ummate I, Ibrahim AG, Musa AH, Medugu JT, Dungus MM, Bukar B, Genesis RY.

Background: A lot of attention has been drawn to primary hyperparathyroidism (PHPT) and vitamin D as risk factors of urolithiasis due to their association with calcium metabolism and stone formation. This study intends to assess the Vitamin D status of stone formers and prevalence of primary hyperparathyroidism amongst them in Maiduguri, Nigeria. A cross-sectional descriptive study was conducted in the University of Maiduguri Teaching Hospital from February 2018 to January, 2019. Eighty five stone formers who consented were recruited. ELISA technique and autoanalyzer (Cobas C311, ISN) was used for sample analysis. IBM SPSS version 26.0 was used for statistical analysis. The prevalence of PHPT in the stone formers was 8.2%. The most common site where stones were found is the kidney (68.2%). A total of 45 (52.9%) have vitamin D3 deficiency or insufficiency, 29 (34.1%) had optimal vitamin D3 levels and 1 (1.2%) had hypervitaminosis D3. Twelve patients had hypoalbuminemia, 24 patients had elevated inorganic phosphate, 8 patients had hypercalcaemia, 17 had hypocalcaemia, while 21 had hyperuricaemia. Given the high incidence of vitamin D deficiency/insufficiency in PHPT in this study and previous findings, evaluating vitamin D and calcium levels could be beneficial for a
thorough assessment of urinary tract stone formers.


Keywords: Urolithiasis, Primary hyperparathyroidism, Vitamin D3 status.

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ORIGINAL ARTICLE


 
 
 

  Emergency Peripartum Hysterectomy in Bowen University Teaching Hospital, Ogbomoso: A 10-Year Retrospective Review

Bobo TI, Bakare TY, Afolabi OA, Adeniji DO, Ladoye OO

Background: Introduction: Emergency peripartum hysterectomy is a life-saving surgical procedure, the procedure is usually performed when all conservative measures have failed to achieve haemostasis during life threatening obstetric haemorrhage. Objective: This was to review emergency peripartum hysterectomy performed in Bowen University Teaching Hospital (BUTH), Ogbomoso, South- West, Nigeria between 1st January, 2014 and 31st December, 2023. Methods: A retrospective review of cases of emergency peripartum hysterectomy between January, 2014 and December, 2023. Result: During the 10- year study period, 6,734 deliveries occurred in the hospital and 42 cases of emergency peripartum hysterectomy were performed giving a prevalence of cases as 0.6% or 6 per 1000 deliveries. The mean age of the studied patients was 35 ± 3.856 years with (28.9%) of the patients being within 26-30 years of age. Majority (71.1%) were multiparous with the modal parity of 3. Majority (63.2%) of the patients were unbooked and fourteen (36.8%) were booked. The leading indication for hysterectomy was uterine rupture 21 (55.3%), 9.4% had maternal death, 54.8% of the patients had stillbirth and 5.3% had early neonatal death. Conclusion: The risk factors associated with EPH should be identified during the antenatal period and pregnant women in high-risk group should be delivered by skilled birth attendants. There is need to enlighten women in our communities on the benefits of antenatal care services and hospital delivery as well as the dangers of delivering under unskilled supervision.


Keywords: Uterine rupture, caesarean section, emergency peripartum hysterectomy, maternal mortality

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ORIGINAL ARTICLE


 
 
 

  Prevalence, Pattern and Risk Factors of Albuminuria among Adults Patients with Sickle Cell Anaemia in Maiduguri, Northeastern Nigeria.

Lawan M, Loskurima U, Ndahi AA, Habib AG, Ladu AI, Shettima J, Amali AO, Chiroma I, Dungus MM, EmeanwuCH, Tijjani ZM, Ummate I

Background: Sickle cell anaemia (SCA)is a common life-threatening haematological disorder that affects millions of people worldwide. Albuminuria has been identified as an early marker of sickle cell nephropathy. The study aimed to determine the prevalence, pattern and risk factors associated with proteinuria among patients with SCA in Maiduguri. Methods: This was a cross-sectional descriptive study that involved 240 patients with SCA attending the heamatology clinic, UMTH and 240 controls with Hb AA that fulfilled the inclusion criteria. The participants were screened for proteinuria (albuminuria or overt proteinuria) using spot urine to assess for albumin creatinine ratio (ACR). The glomerular filtration rate was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Albuminuria was defined as a UACR of 3.4 – 33.9 mg/mmol while overt proteinuria as a UACR of > 33.9mg/mmol. Results: The mean age of the SCA group was 23.95±5.93 years while that of the control group was 24.69±6.58 years (p =0.313). The prevalence of albuminuria and proteinuria were significantly higher among the SCA group compared with the control group, 23.3% vs 10.4% and 12.1% vs 4.2% respectively. (p-value <0.001). Serum creatinine levels correlated positively with albuminuria (r = 0.178; p = 0.006), while PCV correlated negatively with albuminuria (r = -0.178; p=0.006). Albuminuria and high diastolic blood pressure were predictors of kidney disease (odds ratio 0.937, 95% CI 0.019 - 0.981, p = 0.002 and 0.971,95% CI 0.937 - 0.971, p = 0.001 respectively. Conclusion: Albuminuria is a marker of early-stage kidney disease in patients with SCA in Maiduguri. Albuminuria correlates with low PCV and elevated serum creatinine levels in SCA patients.


Keywords: Sickle cell anaemia, Albuminuria, kidney disease, northeastern Nigeria.

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CASE REPORT


 
 
 

  Schwannoma in the Lateral Neck, A Rare Case and Review of the Literature

Arfo FS, Adamu A, Buba B, Shettima HB, Zarami AB

Background: Schwannomas are rare tumours which arise from the sheaths of Schwann cells either from the peripheral, autonomic or central nervous system. It is rare and very few have been reported locally. We report a case of schwannoma, in a 40-year-old woman who presented with a ten-month history of right lateral neck mass which was slow-growing and painless. There were no associated obstructive or toxic symptoms. Examination revealed a well-demarcated right-sided lateral neck mass in zone II of the neck measuring 13 X 6cm, firm, non- tender, not attached to the overlying skin and mobile in the horizontal plane. She had an examination under anaesthesia and total excision of lateral neck mass. Histopathological examination of the mass revealed features in keeping with schwannoma. The patient did well postoperatively.


Keywords: schwannoma, lateral neck mass, histopathology

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CASE REPORT


 
 
 

  Yolk Sac Tumour of Uterine Cervix in a Two-Year-old Girl: A Case Report.

Oduola owoo LT, Oduola owoo BB, Said AA, Rasheed MW, Omidiji O, Odetayo OF, Idowu NA

Background: Germ cell tumour (GCT) of malignant origin is a rare and heterogeneous group of tumours in the paediatric population. It could be seminomatous and non-seminomatous. The non-seminomatous group is less commonly seen. The most commonly seen type under the non-seminomatous group under the age of three years is the yolk sac tumour. The majority of yolk sac tumours is seen in the gonad while very few develop in extra gonadal sites such as the sacrococcygeal region, retroperitoneum, mediastinum, pelvis and stomach among others. Extra gonadal germ cell tumour is extremely rare in the cervix and when it occurs there may be challenges in the management. We report this case due to its rarity and the possibility of cure by chemotherapy, thus preserving fertility. Case Presentation: A 2-year-old female toddler presented with a 9-month history of persistent bleeding and discharge per vagina. At first, the bleeding was once a month and progressively worsened to once a day. There was no change in bowel and urinary habits. There was a pooling of blood in the vaginal vault on pelvic examination, otherwise unremarkable. Abdominopelvic ultrasound scan and magnetic resonance imaging were suggestive of a tumour of the uterine cervix. The mass was excised and sent for histopathological analysis. The histology of the mass showed a yolk sac tumour. Other laboratory investigations including tumour markers were essentially normal. She had treatment with bleomycin, etoposide, and cisplatin regimen (BEP) of chemotherapy as against radical surgery for potential preservation of fertility. She is five years on follow–up at the time of this report. There was no clinical, laboratory, or radiological evidence of recurrence. Conclusion: The 2-year-old female toddler responded well to chemotherapy. This obviated the need for radical surgery. There was preservation of potential for future fertility.


Keywords: Yolk sac, tumour, chemotherapy, uterine cervix.

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bomj Vol 20 No 2

Written by Administrator. Posted in Archives pages

 
 

 

July - December 2023
Volume 20 | Issue 2

This journal has been online since Saturday, April 05, 2013

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ORIGINAL ARTICLES


 
 
 

Knowledge and Attitude of infant Feeding among Health Workers in Private Health Facilities in Ibadan, Oyo State, Nigeria

O. Ariyo, B. O. Olaniyi, O. D. Onojade and F. S. Oladipo

Background: Knowledge and attitude of health workers affect caregivers’ infant feeding practices. However, information on the knowledge and attitudes of health workers in private hospitals is lacking. This study was designed to assess the infant feeding knowledge, attitude, and personal experiences of health workers in private hospitals in Ibadan, Nigeria. This cross-sectional study involved sampling of 108 consenting health workers of registered private health facilities offering ante-natal care services in Ibadan North communities of Oyo State, Nigeria. Data were collected using a semi-structured questionnaire including the socio-demographic characteristics, knowledge, and attitude of infant feeding practices. Knowledge was assessed using a 19-point scale categorized as good (≥13) and poor (<13). Attitude was assessed using a 65-point scale, categorized as good (≥33) and poor (<33). Data were analysed using descriptive statistics at p<0.05. Eighty five percent of the health workers were female, 51.9% were aged 21-30 years, 48.1% were married, and 25.9% were degree holders. Only 47.2% had attended infant feeding training recently, 57.0% had good knowledge and 53.0% had good attitude. Only 30.6% knew early initiation of breastfeeding, and 30.6% knew continued breastfeeding up 24 months and beyond. Just 49.1% considered breastfeeding in public non-embarrassing, and 33.3% agreed that infants less than six months should not be given water. There is evidence of limited knowledge and poor attitude towards the recommended infant feeding practices among the health workers in private health facilities in Ibadan. Periodic training on infant feeding for health workers in private health facilities is hereby recommended.

Key words: Exclusive breastfeeding, early initiation, private hospital, personal experience

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SHORT COMMUNICATION


 
 
 

Health Issues of Nigerian Muslim Pilgrims in The Immediate Post Covid- 19 Era Hajj Year 2022 in the Kingdom of Saudi Arabia

Raji S.O., Ismaila A.I., Amina S.M., A. Adam.

Introduction: Hajj and Umrah are the main pilgrimages recommended in the Islamic faith to be performed at least once in a lifetime by those who have the wherewithal. It is one of the largest mass gatherings worldwide. 1 Muslims all over the world (over 180 countries) visit the Great Holy Mosque in the city of Mecca to perform the prescribed religious rites of the main pilgrimage (Hajj) which spans the second week of the twelfth month (Zul-hijja) of the Islamic lunar Calendar. The lesser/minor pilgrimage (Umrah) can be performed at any time of the year. Most hujajs (pilgrims) from outside Saudi Arabia perform Umrah and Hajj in a single journey (tamatui). Some faithfuls also perform the lesser pilgrimage (Umra) in the last ten days of the month of Ramadan (9 th month of the Islamic lunar calendar) due to the additional merits and blessings of this last third of the fasting month and additional opportunity of performing other meritorious and rewarding acts of worship such as i'tikaf (seclusion) in the Great Holy Mosque.

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CASE REPORT


 
 
 

Unusual sequelae of persistent digit sucking Habit Facial Hyperkeratosis/Hyperpigmentation

Umweni A.A, Otaren N.J.

Background: Although digit sucking is normal in infants and young children, prolonged duration of these habits might have consequences for the developing orofacial structures and occlusion. It is advisable to intercept the habit between the ages of 4 and 7 years. We report the case of a 9 year old boy who presented with a history of chronic digit sucking habit with associated hyperkeratosis/hyperpigmentation of the left cheek from repeated mechanical trauma from his left ring finger while he sucked his left index and middle fingers. The lesion is about 5mm in diameter. Full orthodontic assessment of the patient was carried out and habit breaking appliance instituted after counseling mother and child. Occlusal problems were reversed after habit cessation. Six months after breaking the habit, the hyperkeratosis/hyperpigmentation of the left cheek was still present even though it is reduced. This is an unusual finding in a child with chronic digit sucking habit.

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CASE REPORT


 
 
 

Spondylocostal Dysostosis: Mild variant in a Nigerian Newborn

Umar H.U., Mohammed L.M., Farouk A.G., Mustapha Z.

Background: Spondylocostal dysostosis (Jarcho-Levin Syndrome) is a rare congenital abnormality of spines and ribs which usually presents with trunk dwarfism, scoliosis, and respiratory symptoms. Its occurrence can be sporadic or familial. The clinical characteristics are vertebral abnormalities of hemivertebrae, butterfly vertebrae, scoliosis and variable rib abnormalities. Imaging is critical in its evaluation and management. Case Presentation: A 4-day-old child of a non-consanguineous couple delivered with swelling at the back. The family history was unremarkable for congenital anomalies. Clinical examination and radiological findings was consistent with spondylocostal dysostosis. Conclusion: Spondylocostal dysostosis is a rare musculoskeletal abnormality. Imaging plays a vital role in its diagnosis. An early diagnosis is necessary to prognosticate and institute appropriate management.

Key words: Spondylocostal dysostosis, Jarcho-Levin, Hemivertebrae , Rib anomalies, Congenital scoliosis.

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CASE REPORT


 
 
 

A Huge Submucosal Fibroid Polyps; A Hidden Cause of Necroturia

Muhammad A.S., Aminu M.B., Dattijo L.M., Oluwagbemiga U.O., Ezugwu O.P.

Background : Fibroids are benign neoplasms of the uterus arising from smooth muscle. They are also termed uterine leiomyomas. It is the most common growth found in the female reproductive system and may undergo malignant transformation in less than 1% of cases to form leiomyosarcoma. Fibroids may present with abnormal uterine bleeding and pelvic pressure symptoms. Fibroid polyp can be a cause for concern especially if it grows so large to cause symptoms of obstructive uropathy. Thus, the patient may present with dysuria, anuria, or even necroturia as seen in our patient. Case summary: We present a case of 40-year-old P 5 + 0, A 3 lady, whose last childbirth was 10 years before presentation. She presented with 3 years history of recurrent vaginal bleeding, dizziness, and a mass protruding through her vagina. Her packed cell volume was 14%. She was fully investigated and upon catheterization, nectroturia was observed. She was counselled and had vaginal polypectomy. Conclusion: Necroturia associated with uterine fibroid polyp is a rare occurrence, hence physicians should have a high index of suspicion when evaluating patients with necroturia.

Keywords: Submucosal Fibroid Polyps, Nectroturia, Foley Catheter

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ORIGINAL ARTICLE


 
 
 

Assessment of Right Ventricular Systolic Function Using Tissue Doppler-Derived Tricuspid Lateral Annular Systolic Velocity (S`) Among HIV Patients on Highly Active Antiretroviral Therapy (HAART) And Its Relationship with CD4 Cell Count and Viral Load

Baba M.M., Buba F., Talle M.A., Garbati M.A, Abdul H., Mairari F.G.

Background : Human immunodeficiency virus-infected patients are at increased risk of cardiovascular diseases compared with the general population, and right ventricular systolic dysfunction is said to be associated with poor outcomes. We therefore assessed right ventricular systolic function using tissue Doppler-derived tricuspid lateral annular systolic velocity (S`) among HIV-infected patients on highly active antiretroviral therapy (HAART). We evaluated its relationship with viral load and cd4 cells count. Methods: The study was a cross-sectional conducted among HIV-infected patients receiving HAART at the Federal Medical Centre, Nguru, Yobe State, Northeastern Nigeria using tissue Doppler-derived tricuspid lateral annular systolic velocity (S`). Results : One hundred and seven (107) subjects were recruited into the study comprising thirty-seven (34.6%) males and seventy (65.4%) females. Ninety-six (89.71%) had preserved right ventricular systolic function (RVSF) while 11(10.28%) had reduced RVSF. The mean CD4 cells count of patients with preserved RVSF and those with reduced RVSF were 838.37±27.50 and 301.66±12.38 respectively (P = <0.001). Similarly, the mean viral load of patients with preserved and reduced RVSF were 547.90±10.75 and 10293.00±74.67 respectively (P = <0.001). Pearson Correlation analysis between CD4 cell count and S` revealed a positively significant relationship (r = 0.894, P = < 0.001); while the relationship between viral load and S` was negative but significant (r = -0.879, P = < 0.001). Conclusion: The prevalence of right ventricular systolic dysfunction among patients with HIV on HAART was found to be 10.28%. There was a positive and significant correlation between the parameter of RVSF (tissue doppler derived tricuspid lateral annular systolic velocity) with CD4 cell count and a negative but significant correlation with HIV viral load.

Keywords: Right ventricular systolic function, Tissue Doppler derived lateral tricuspid annular systolic velocity (S`), CD4 cells, viral load.

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bomj Vol 20 No 1

Written by Administrator. Posted in Archives pages

 
 

 

January - June 2023
Volume 20 | Issue 1

This journal has been online since Saturday, April 05, 2013

PDF access
This Journal allows immediate access to content in HTML + PDF for both current and archived editions.

Mobile access
Full text of the articles can be accessed via our android application and mobile site free of charge.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License

 

PRELIMINARY PAGES

 

ORIGINAL ARTICLES


 
 
 

Asymptomatic Bacteriuria and Foetomaternal Outcome at the University of Maiduguri Teaching Hospital

Kwari SD, Chama CM, Gadzama GB

Background: Asymptomatic bacteriuria (ASB) is a common medical complication of pregnancy and may be associated with acute pyelonephritis, preterm labour and delivery, intrauterine growth restriction (IUGR), low birth weight (LBW), anaemia, hypertension and long-term renal dysfunction. Routine screening and treatment of ASB in pregnancy are recommended. Objectives: This study determined the prevalence, common organisms implicated, their antibiotic sensitivity pattern and the foetomaternal outcome of pregnant women with ASB. Methods: We conducted a prospective study at the Department of Obstetrics and Gynaecology, University of Maiduguri Teaching Hospital (UMTH), Maiduguri, Nigeria. One hundred and fifty pregnant women attending antenatal booking were consecutively recruited. We collected demographic and clinical information. A clean catch midstream urine specimen was collected for culture and sensitivity. The women were followed up to delivery and foetomaternal outcome were obtained. Results: The prevalence of ASB was 22%. Escherichia Coli was the most predominant organism isolated in 45.4%. Nitrofurantoin (90.9%), Ceftriaxone (87.8%) and Co-Amoxiclav (84.8%) showed the highest activity against the isolated microbes and were resistant to Ampicillin (87.9%) and Cloxacillin (79.7%). ASB is associated with an increased risk for UTI (P-value = 0.001), pyelonephritis (0.002), anaemia later in pregnancy ( ? 0.001), preterm delivery ( ? 0.001), low birth weight ( ? 0.001) and admission to SCBU (0.023). Conclusion: The prevalence of ASB is high and associated with significant maternal and perinatal morbidity. We recommend screening all pregnant women attending antenatal clinics for ASB and appropriate treatment given.

Key words: Asymptomatic bacteriuria, pregnancy, prevalence, foetomaternal outcome, urine culture, Nigeria.

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ORIGINAL ARTICLES


 
 
 

Elective Gynaecological Surgeries in Aminu Kano Teaching Hospital, Kano, Nigeria: a 5-year review

Usman AU, Natalia A, Ibrahim DM

Background: Elective surgeries include procedures done to correct non-life-threatening medical problems as well as to alleviate conditions causing psychological stress or other potential risks to patients. This study described the pattern of elective Gynaecologic surgeries conducted in Obstetrics and Gynaecology department of Aminu Kano Teaching hospital, over a five-year period. Objective: To describe the pattern of elective gynaecologic surgeries conducted in Obstetrics and Gynaecology Department of our hospital over a five-year period. Methods: A retrospective study of all elective surgical procedures conducted at the Obstetrics and Gynaecology department of Aminu Kano Teaching hospital from 1st September, 2012 to 31st August, 2017 was conducted. Theatre operation register and gynaecological ward admission records were retrieved and reviewed. Information extracted include: age of patient, indication for the surgery, type of surgery conducted, nature of procedure (minor, intermediate and major), the cadre of surgeon and assistant(s) performing the surgery and the type of anaesthesia used for the surgery. Results: The total number of elective gynaecologic surgeries conducted over the study period was eight hundred and two (802) accounting for 19.4% of all surgical procedures. Uterine fibroid was the commonest indication for surgery with myomectomy being the commonest surgical procedure performed constituting 181(30%) of all gynaecologic operations. Hysterectomy was the second commonest procedure 115 (19%) indicated most commonly by uterine fibroids 53(46%). Conclusion: This study demonstrated 19.4% prevalence of elective gynaecological procedures in our centre. Consultants are the leading surgeons in most of the procedures and a significant association was found between the nature of the procedure and the cadre of surgeon. There is need to strengthen the postgraduate training of Resident doctors by exposing them to more hands-on training on major procedures.

Key words: Elective, gynaecological surgery, procedure

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLES


 
 
 

Prevalence and risk factors/predictors of seizure-related injuries among children with Epilepsy at the University of Benin Teaching Hospital, Benin City.

Okunola P.O. Ani C.K

Background: Children with epilepsy are considered to be at an amplified risk for injuries as compared to the general population. The increased risk may occur directly as a result of the seizure or due to other comorbid conditions that predispose to injuries. Objectives: This study aimed to determine the frequency and the pattern of seizure-related injuries in children aged 0-17 years with epilepsy seen at the University of Benin Teaching Hospital, (UBTH), Benin City, Nigeria. Methods: Consecutive cases of children with epilepsy seen at the Paediatric Neurology Clinic of UBTH, Benin-City over a period of 6 months were evaluated for injuries in the preceding 12 months using a structured questionnaire. Results: A total of 119 respondents were involved in the study, 50 (42.02%) sustained an injury at some point in the preceding 12 months. Participants in the middle socio- economic class had more seizure-associated injuries (n = 25, 59.5%), compared to those in the low socio-economic class (n = 20, 42.0%) and high socio-economic class (n = 5, 18.5%); P = 0.003. Seizure-related injuries were associated most with generalized seizure (50.5%) when compared with focal seizures (14.3%) P = 0.001. Among the subjects, a tonic-clonic seizure was the most common subtype of generalised seizure (p =22.306, p = < 0.001). The commonest seizure-related injuries are skin bruises (35.1%), followed by soft tissue lacerations (22.8%). Strong association between epilepsy-related injuries and compliance to anti-epileptic drugs (AEDs) were noted. Conclusion: Children with epilepsy are at higher risk of injury and this risk is modified by some factors like socioeconomic status, seizure type, and compliance with medication

Key words: Seizure, Children, Injuries, Epilepsy

[FULL ARTICLE (PDF)]

ORIGINAL ARTICLES


 
 
 

Complications of Ventriculoperitoneal Shunt for Infantile Hydrocephalus: A Single Nigerian Centre Experience

Usman B, Abubakar AM

Background: Ventriculoperitoneal shunt (VP–shunt) is one of the easiest and most common ways of treating hydrocephalus worldwide. Common post-operative complications include shunt malfunction (obstruction, disconnection, fracture), infection of skin and hardware, exposed/extruded shunt, calcification and per anal extrusion. Objectives: A 5-year retrospective review of all complications observed among infants with VP Shunt in our centre. Methods: The study period was between July 2017 and June 2022. Extracted data included: Demographic data on the Age and sex at presentation, type of Hydrocephalus, and the observed complications. Results: Forty-six infants comprising 32 (70%) boys and 14(30%) girls had VP Shunt, with ages (number) of < 1 month (26.1%), 1 – 6 Months (43.5%), and 7 – 12 Months (30.4%). Types of Hydrocephalus were congenital (A. S. in 13, NTD associated in 18) and acquired (post meningitis in 13, IVHP in 2). Complications were observed in eight (17.4%), consisting of 6(75%) Males and 2(25%) Females, with M: F of 3:1. Complications among the eight (8) patients include: Shunt Obstruction (50.0 %), Shunt Disconnection (12.5 %), Shunt Infection (50.0 %), Skin Infection (25.0 %), Shunt calcification ( 12.5 %), Exposed Shunt( 12.5 %), Extruded Shunt (12.5%), Per anal protrusion (12.5 %) and Death (25.0 %). Conclusions: Outcomes were very good, with few manageable complications.


Keywords: Children, Complications, Hydrocephalus, Infants, VP – Shunt

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ORIGINAL ARTICLES


 
 
 

Twenty Years of Experience with Lichen Planus in Kaduna, North-West Nigeria

Husain Yahya

Background: Background: Lichen planus (LP) is a chronic inflammatory papulosquamous autoimmune disease which predominantly affects the skin but may also affect mucous membranes and nails. It is commoner in adults and occurs in all races. Reports about LP from northern Nigeria are scanty. Objective: To report the relative prevalence, duration, clinical presentation, and outcome of treatment for patients with LP seen over 20 years. Methods: Retrospective review of records of patients diagnosed with LP in two dermatology clinics in Kaduna, Nigeria from September 2001 – August 2021. Results: Of 39,037 patients with new skin disease, 335 (0.9%) were diagnosed with LP: mean age 37.6 years (range 5 -81), 11.3% < 18 years and 55% < 40 years, male- female ratio 1:1. The median duration at presentation was 8 weeks (75% = 16 weeks). The lower legs (65%), lower arms (61.2%), abdomen (31.6%), upper arms (29%), upper back (28.1%), lower back (27.2%), chest (22.4%) and thighs (21.5%) were the most frequently affected sites. The oral mucosa, penis and nails were affected in 6, 9 and 2 patients only. Itching (97%), hyperpigmentation (26.6%), and Koebner’s phenomenon (23%) were also present. Classic LP accounted for 88.1% while hypertrophic LP (12.5%) and annular LP (6.3%) were other variants, some patients with multiple variants. Just over 7 % of patients had previous disease (median interval 7 years). Hepatitis C virus antibody was positive in 6.2%. All patients were treated with topical steroids but 45% required oral prednisolone. On follow-up, LP had resolved in 79.4% of patients. Conclusion: Lichen planus affected a younger population, presented in a classic way in most patients, affected the oral and other mucosae much less frequently and responded well to topical and systemic steroids.


Key words: Lichen planus, clinical presentation, Kaduna-Nigeria

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CASE REPORT


 
 
 

Symmetrical Peripheral Gangrene Resulting from the Application of Henna: A Rare Clinical Occurrence

Abdullahi MA, Kabir MA, Mustapha MI, Mamuda AA, Shamsudeen MB

Background: Symmetrical peripheral gangrene (SPG) is a rare clinical entity leading to ischemic necrosis of extremities. We report a case of SPG in patient brought into the orthopaedic clinic of Aminu Kano Teaching Hospital (AKTH), Kano, two days after applying a beautification substance called Henna. Case Summary: We report a case of a 28-year-old lady who presented at the emergency department of AKTH with a complaint of extreme pains in both hands and feet. The patient noticed a gradual darkening of the fingers and toes two days after applying the Henna, associated with severe pain at rest. She was thoroughly evaluated and examined for other possible risk factors or illnesses, but none was found. The patient was counselled and she subsequently consented to amputation. The gangrenous parts of the digits of her fingers and the tarsometatarsal of her feet were amputated bilaterally and the procedure was carried out successfully. Conclusion: To our knowledge, this is the first case report of symmetrical peripheral gangrene occurring after routine application of Henna as a beautification agent. No other possible risk factor was identified. We highlight the possibility of a beautification agent (Henna) as a causative factor of SPG. Thus, women should be careful of the mixtures in Henna that could lead to SPG.


Key words: Symmetrical, Bilateral, Gangrene, Henna, Amputation

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